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Long-term prognosis of patients with congestive heart failure
M Matoba1, S Matsui, T Hirakawa
1Department of Cardiology, Kanazawa Medical University, Ishikawa, Japan.
Insights
Prognosis in congestive heart failure (CHF) depends on functional status and underlying heart disease. Left ventricular function and ventricular tachycardia presence significantly impact long-term survival rates in CHF patients.
Area of Science:
- Cardiology
- Internal Medicine
- Clinical Research
Background:
- Congestive heart failure (CHF) is a complex clinical syndrome with significant morbidity and mortality.
- Identifying prognostic factors is crucial for effective patient management and treatment strategies.
Purpose of the Study:
- To evaluate factors influencing long-term prognosis in patients with recent-onset congestive heart failure.
- To determine the relationship between clinical variables and survival rates in a CHF cohort.
Main Methods:
- Prospective evaluation of 100 patients with recent-onset congestive heart failure.
- Analysis of survival rates at 1, 3, 5, and 10 years.
- Correlation analysis between prognostic indicators and cumulative survival.
Main Results:
- Overall 10-year survival rate was 14.7%.
- Prognosis was poorer in patients with coronary artery disease or cardiomyopathy compared to other heart diseases.
- NYHA class III/IV, reduced left ventricular stroke work, and ventricular premature depolarization were associated with lower survival rates.
Conclusions:
- Functional status (NYHA class), underlying etiological heart disease, left ventricular stroke work, and ventricular tachycardia are key determinants of long-term prognosis in CHF.
- These factors provide critical information for risk stratification and management of congestive heart failure.
Abstract:
Factors determining prognosis in 100 patients with recent onset of congestive heart failure (CHF) were evaluated. The 1 year, 3 year, 5 year, and 10 year survival rates in the entire CHF group were 78.5%, 59.8%, 50.4% and 14.7%, respectively. No correlations between age, sex, heart rate and cardiothoracic ratio, and the cumulative survival rate were found. The prognosis of patients with CHF due to underlying coronary artery disease or primary cardiomyopathy was poor compared with that of patients with other types of heart disease. Patients whose NYHA classification was class III or VI had a significantly lower survival rate than those in class II. Patients with lower left ventricular stroke work and consecutive ventricular premature depolarization also had a significantly lower survival rate. These results suggest that functional status, underlying heart disease, left ventricular stroke work, and the presence of ventricular tachycardia provide important information regarding the long-term prognosis in patients with congestive heart failure.