Bioinformatics identification of antigenic peptide: predicting the specificity of major MHC class I and II pathway

Ole Lund1, Edita Karosiene2, Claus Lundegaard3

  • 1Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Kongens Lyngby, Denmark. lund@cbs.dtu.dk.

Bioinformatics methods for immunology have become increasingly used over the last decade and now form an integrated part of most epitope discovery projects. This wide usage has led to the confusion of defining which of the many methods to use for what problems. In this chapter, an overview is given focusing on the suite of tools developed at the Technical University of Denmark.