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Bacterial protein N-glycosylation: new perspectives and applications

Harald Nothaft1, Christine M Szymanski

  • 1Alberta Glycomics Centre and Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada. nothaft@ualberta.ca

The Journal of Biological Chemistry
|January 19, 2013
PubMed

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Oligosaccharide Assembly

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Proteoglycans

Glycans, a class of complex heterogeneous molecules, can be covalently attached to proteins to form glycosylated proteins that regulate various physiological and pathological processes. Glycosylated proteins or glycoproteins comprise N-linked and O-linked oligosaccharides. O-glycosylation is the most common type of protein glycosylation. Here, glycans attach to the oxygen atom of the hydroxyl groups of Serine or Threonine residues. O-linked glycosylation occurs later in protein processing,...
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Protein Modifications in the RER

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Bacterial Translocation and Protein Secretion

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