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Updated: Oct 13, 2026
09:25
Bioluminescent Orthotopic Model of Pancreatic Cancer Progression
Published on: June 28, 2013
Carcinoma of the pancreas: are we making progress?
1Department of Surgery, Johns Hopkins Medical Institutions, Baltimore.
Maryland Medical Journal (Baltimore, Md. : 1985)
|April 1, 1990
Abstract:
Over the past several decades no disease has frustrated clinicians more than carcinoma of the pancreas. At the time of diagnosis most patients have been unresectable. Recent reports suggest that when resection is possible, pancreaticoduodenectomy can be performed safely and survival extended by adjuvant therapy.
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Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment: