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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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An &#8220;All-laser&#8221; Endothelial Transplant
09:59

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Corneal endothelial changes after selective laser trabeculoplasty.

Keith Ong1, Lillian Ong, Leonard Ong

  • 1Department of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia. drkeithong@optusnet.com.au

Clinical & Experimental Ophthalmology
|January 22, 2013
PubMed
Summary

Selective laser trabeculoplasty may cause temporary whitish spots in the corneal endothelium. These spots typically resolve within a month, suggesting minimal long-term effects on normal corneas.

Keywords:
corneal endotheliumglaucomalaser surgery

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Area of Science:

  • Ophthalmology
  • Glaucoma Treatment
  • Corneal Health

Background:

  • Whitish spots observed in corneal endothelium post-selective laser trabeculoplasty (SLT).
  • Corneal specular microscopy is utilized to assess endothelial changes after SLT.

Purpose of the Study:

  • To evaluate the transient effects of SLT on the corneal endothelium.
  • To determine the potential risks of SLT in patients with compromised corneas.

Main Methods:

  • Prospective observational study involving 15 open-angle glaucoma patients.
  • Corneal specular microscopy performed before, immediately after, and 1 month post-SLT.
  • SLT parameters: 50±5 shots, 180° meshwork, 0.3-0.9 mJ power.

Main Results:

  • Three patients showed numerous, four showed few, and eight showed no dark spots post-SLT.
  • All observed dark spots resolved completely by the 1-month follow-up.

Conclusions:

  • SLT's impact on corneal endothelium appears transient in normal corneas.
  • Potential risk of endothelial compromise exists in compromised or pigmented corneas, especially with repeated SLT.
  • Further studies needed; minimize SLT energy and shots until then.