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Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
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Nitrogen dioxide inhalation induces genotoxicity in rats

Ming Han1, Zhen Guo, Guangke Li

  • 1College of Environment and Resource, Center of Environmental Science and Engineering, Shanxi University, Taiyuan, Shanxi 030006, PR China.

Chemosphere
|January 22, 2013
PubMed
Summary

Nitrogen dioxide (NO2) inhalation causes DNA damage and increases micronucleus frequency in rats. These genotoxic effects show a clear dose-dependent relationship, indicating NO2 is a genotoxic agent.

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