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[Antimicrobial action of new imidazolinium compounds]
Z Kuncewicz1, J Krysiński, J Pernak
1Institut für Chemische Technologie der Technischen Universität, Poznań, Polen.
Die Pharmazie
|January 1, 1990
Abstract:
Syntheses and antibacterial activity of 1-ethyl-2-alkyl-3-(alkoxymethyl)- and 1-ethyl-2-alkyl-3-(alkylthiomethyl)imidazolinium chlorides are described. Syntheses of the imidazolinium compounds were performed by reaction of 1-ethyl-2-alkylimidazoline with chloromethylalkyl ether or with chloromethylalkyl sulfide. Antimicrobial properties of obtained compounds was tested on 13 strains of bacteria and fungi. Chlorides with alkylthiomethyl residue showed the highest antimicrobial activity.