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Antiretroviral therapy adherence support: recommendations and future directions
K Rivet Amico1, Catherine Orrell
1Center for Health, Intervention and Prevention, University of Connecticut, Storrs, CT 06269, USA. rivetamico@comcast.net
This review synthesizes evidence on intervention approaches for antiretroviral therapy (ART) adherence. It highlights the need to align research with practice by understanding intervention drivers and integrating real-world evidence.
Area of Science:
- Public Health
- Behavioral Science
- Health Services Research
Background:
- Growing evidence base for interventions supporting antiretroviral therapy (ART) adherence.
- Numerous reviews, syntheses, and guidelines exist, necessitating a literature characterization.
- Need to align current research and practice for effective ART adherence support.
Purpose of the Study:
- To characterize the current literature on ART adherence interventions.
- To identify research gaps and areas for targeted focus.
- To provide recommendations for intervention development and implementation.
Main Methods:
- Systematic literature review and synthesis of intervention approaches for ART adherence.
- Analysis of intervention outcomes and effect drivers from controlled research.
- Identification of strategies for individuals, communities, and systems.
Main Results:
- The literature on ART adherence interventions is extensive but requires focused direction.
- Understanding the 'drivers' of intervention effects is crucial for identifying optimal strategies.
- A gap exists in integrating evidence from practice into research agendas.
Conclusions:
- Aligning research and practice is critical for advancing ART adherence support.
- Future research should focus on intervention mechanisms and context-specific effectiveness.
- Integrating real-world evidence into research agendas will foster synergy between practice and research communities.
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