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Updated: May 15, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
The next questions in chronic myeloid leukaemia and their answers
David Marin1, Antonia Rotolo, Dragana Milojkovic
1Department of Haematology, Imperial College London, Hammersmith Hospital London, UK. d.marin@imperial.ac.uk
Purpose Of Review:
In this review, we analyze some of the topical issues in the clinical management of chronic myeloid leukaemia (CML).
Recent Findings:
In recent years, the management of CML patients has increased in complexity as molecular monitoring has brought to the clinical scene new therapeutic targets and the second-generation tyrosine kinase inhibitors have been licensed for first-line use.
Summary:
In this article, we will try to answer some of the questions that a practising physician may face in clinical practice, such as: What should be the aim of therapy? What is the best front-line therapy? Which patients should receive an allogeneic stem cell transplant?
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