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Related Concept Videos

Caspases01:24

Caspases

Caspase, a family of cysteine proteases, serve as effectors in apoptosis. The ced3 gene in C.elegans was first identified to be involved in apoptosis. This gene encodes the ced-3 caspase that is similar to the interleukin-1-beta converting enzyme or ICE in mammals. In addition to apoptosis, caspases also function in the inflammatory response. Inflammatory caspases are essential in activating pro-inflammatory cytokines that recruit immune cells and block the replication of pathogens inside cells.

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In Vitro Cleavage Assays using Purified Recombinant Drosophila Caspases for Substrate Screening
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MerCASBA: an updated and refined database of caspase substrates

Arthur Fridman, Irene Pak, Brent D Butts

    Apoptosis : an International Journal on Programmed Cell Death
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    PubMed
    Summary

    No abstract available in PubMed .

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