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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Learning from an epidemiological, population-based study on prescribed medicine use in adults
Kerena A Eckert1, Zumin Shi, Anne W Taylor
1Population Research and Outcome Studies, Discipline of Medicine, University of Adelaide, Adelaide, South Australia, 5005, Australia. kerena.eckert@adelaide.edu.au
This study found no overall increase in prescribed medicine use in Australian adults between 2004 and 2008. However, medicine use decreased in younger and older adults, while increasing in middle-aged adults, highlighting varied trends in medication management.
Area of Science:
- Public Health
- Pharmacology
- Gerontology
Background:
- Prevalence of prescribed medicine use is a key indicator of population health and healthcare utilization.
- Understanding trends in medication use is crucial for effective healthcare planning and resource allocation.
Purpose of the Study:
- To examine changes in the prevalence of prescribed medicine use in Australian community-based adult populations between 2004 and 2008.
- To identify demographic and therapeutic group-specific trends in medication consumption.
Main Methods:
- Face-to-face interviews were conducted with random, representative samples of South Australian adults aged 15 years and older in 2004 and 2008.
- Data collected included self-reported use of prescribed medicines, common medicine categories, and polypharmacy (use of multiple medicines).
- Participation rates were 76% in 2004 and 73% in 2008.
Main Results:
- Overall prevalence of using one or more prescribed medicines remained stable (46.8% vs 47.3%).
- Significant reductions in medicine use were observed in younger adults (15-24 years) and older adults (≥65 years).
- A significant increase in medicine use was noted in the 35-44 years age group, while respiratory and musculoskeletal medicine use decreased.
Conclusions:
- The study highlights varying patterns of prescribed medicine use across different adult age groups in Australia.
- Findings suggest a need to address de-prescribing, monitor for adverse events, and consider the economic impact of medication use.
- This research provides insights into the quality use of medicines within the Australian population.
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