Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 15, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Multiple primary malignant neoplasms: multi-center results from Turkey.

N A Babacan¹, S Aksoy, B Cetin

¹Cumhuriyet University Faculty of Medicine, Department of Medical Oncology, Sivas, Turkey.

Journal of B.U.ON. : Official Journal of the Balkan Union of Oncology

|January 22, 2013

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Antibody-drug conjugate sequencing in HER2-positive metastatic breast cancer: Real-world outcomes of trastuzumab deruxtecan with and without prior T-DM1 exposure.

Breast (Edinburgh, Scotland)·2026

Same author

QuiCAT: a scalable and flexible framework for mapping synthetic sequences.

Bioinformatics (Oxford, England)·2025

Same author

Health-related quality of life outcomes from KEYNOTE-412: chemoradiotherapy with or without pembrolizumab in participants with head and neck squamous cell carcinoma.

Frontiers in oncology·2025

Same author

SYNCHRONOUS ONCOCYTIC CARCINOMA, MEDULLARY CARCINOMA AND PAPILLARY MICROCARCINOMA OF THYROID.

Acta endocrinologica (Bucharest, Romania : 2005)·2025

Same author

In vitro antifungal susceptibility of the dermatophytes: a single center study from Eastern Black Sea Region of Turkey.

European review for medical and pharmacological sciences·2024

Same author

Cone-beam-computed tomography evaluation of mandibular nutrient canals in patients with periodontal diseases.

Nigerian journal of clinical practice·2023

The frequency of multiple primary malignant neoplasms (MPMNs) is increasing. This study identified common second primary cancer (SPC) pairs, like breast-gynecologic in females and head and neck-lung in males, emphasizing rigorous evaluation of suspicious lesions.

Area of Science:

Oncology
Cancer Epidemiology

Background:

Multiple primary malignant neoplasms (MPMNs) involve diagnoses of two or more independent primary malignancies.
The incidence of MPMNs is rising globally.
Understanding the patterns of second primary cancers (SPCs) is crucial for patient management.

Purpose of the Study:

To determine the frequency of SPCs in patients with MPMNs.
To identify the clinical features and common combinations of SPCs.
To raise physician awareness regarding SPC probabilities.

Main Methods:

Retrospective analysis of MPMN patients diagnosed between January 1990 and December 2010.
Data collected from hospital charts across five centers.
Evaluation of 377 patients with MPMNs.

More Related Videos

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker

Published on: September 15, 2023

Related Experiment Videos

Last Updated: May 15, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker

Published on: September 15, 2023

Main Results:

The most frequent initial cancers were head and neck, breast, and colorectal.
The most common SPCs were lung, colorectal, and breast cancers.
In females, common pairs included breast-gynecologic cancers; in males, head and neck-lung cancers were most frequent.

Conclusions:

Physicians must maintain high awareness of SPC probabilities.
Suspicious lesions in patients with a history of cancer warrant thorough evaluation.
Extensive histopathologic assessment is recommended for suspected second tumors.