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Related Experiment Video

Updated: May 15, 2026

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum

Published on: February 15, 2015

Seeking a unified framework for cerebellar function and dysfunction: from circuit operations to cognition.

Egidio D'Angelo¹, Stefano Casali

¹Department of Brain and Behavioral Sciences Pavia, Italy ; IRCCS C. Mondino, Brain Connectivity Center Pavia, Italy.

Frontiers in Neural Circuits

|January 22, 2013

Summary

The cerebellum, known for motor control, also processes cognition and emotion via common computational schemes. Its distinct connectivity enables diverse functions, potentially explaining its role in various brain disorders.

Keywords:

autism cerebellum cognition dyslexia motor control prediction schizophrenia timing

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Area of Science:

Neuroscience
Cognitive Neuroscience

Background:

The cerebellum's role traditionally focused on sensory-motor coordination and learning.
Emerging evidence suggests cerebellar involvement in cognitive and emotional processing.

Purpose of the Study:

To explain the cerebellum's diverse functional roles beyond motor control.
To propose a conceptual framework for understanding cerebellar contributions to cognition and emotion.

Main Methods:

Review of anatomical data on cerebellar connectivity.
Development of a meta-levels conceptual framework.

Main Results:

Cerebellar functions may arise from similar circuit structures operating with a common computational scheme.
Specific connectivity of cerebellar modules to different cerebro-cerebellar loops underlies segregated motor, cognitive, and emotional functions.
An interplay between timing and learning is central to cerebellar mechanisms across multiple levels.

Conclusions:

The cerebellum acts as a general-purpose co-processor, with its effects modulated by connected brain centers.
Dysfunction in cerebro-cerebellar loops may contribute to neurological and psychiatric disorders like dyslexia, autism, schizophrenia, and depression.