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(iv) Enhancing the safety and reliability of joint replacement implants
Louise M Jennings1, Mazen Al-Hajjar, Claire L Brockett
1Principal Research and Innovation Fellow, Institute of Medical and Biological Engineering iMBE, University of Leeds, Leeds, UK and Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospital Trust, Leeds, UK. Conflict of interest: none.
None:
A new Stratified Approach For Enhanced Reliability (SAFER) pre-clinical simulation testing of joint prostheses is presented in this article. The aim of this approach is preclinical systematic testing of wear performance in the much wider envelope of conditions found clinically rather than relying only on the standard testing conditions that are currently used. The approach includes variations in surgical delivery, variations in kinematics, variations in the patient population and degradation of the biomaterial properties. Clinical experience of existing prostheses has been used to validate the new in vitro methods.
