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Reply: To PMID 22483652

Matthew J Schuchert, Rodney J Landreneau

    The Annals of Thoracic Surgery
    |January 23, 2013
    PubMed
    Summary

    No abstract available in PubMed .

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    Drug Metabolism: Phase II Reactions01:14

    Drug Metabolism: Phase II Reactions

    Phase II reactions are essential for the detoxification and elimination of drugs from the body. These reactions involve the conjugation of parent drugs or their phase I metabolites with endogenous molecules, resulting in more hydrophilic drug conjugates. The primary conjugation reactions in this phase are sulfation and glucuronidation. Both sulfation and glucuronidation typically produce biologically inactive metabolites. However, in some cases involving prodrugs, active metabolites may be...

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