Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Aneurysm I: Introduction

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...

Aneurysm III: Interprofessional Care

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...

Hemorrhagic Stroke l: Introduction

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...

Hemorrhagic Stroke ll: Pathophysiology

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...

Disorders of Hemostasis

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Subchondral Bone Injections for the Treatment of Knee Osteoarthritis.

The archives of bone and joint surgery·2026

Same author

Clinical, Functional and Radiological Results of Bicondylar Tibial Plateau Fractures (AO41.C) Treated by Osteosynthesis with Plates and Screws.

The archives of bone and joint surgery·2026

Same author

Circumstances that Increase the Risk of Periprosthetic Joint Infection after Total Knee Arthroplasty.

The archives of bone and joint surgery·2026

Same author

Is Pharmacologic Prophylaxis for Venous Thromboembolism Necessary in People With Hemophilia After Total Knee and Hip Arthroplasty?

The archives of bone and joint surgery·2026

Same author

Robotic-assisted Total Knee Arthroplasty versus Conventional Total Knee Arthroplasty.

The archives of bone and joint surgery·2026

Same author

Total Ankle Replacement in Hemophilia.

The archives of bone and joint surgery·2025

Search research articles

Related Experiment Video

Updated: May 15, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

Pseudoaneurysms in haemophilia.

E Carlos Rodriguez-Merchan¹

¹Department of Orthopaedic Surgery, La Paz University Hospital, Paseo de la Castellana 261, Madrid, Spain. ecrmerchan@gmx.es

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis

|January 23, 2013

Summary

This summary is machine-generated.

Pseudoaneurysms are rare in haemophilia patients but require prompt diagnosis following arterial trauma. Less invasive treatments like endovascular options are now preferred, alongside essential haemostasis management.

More Related Videos

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Published on: August 30, 2020

Related Experiment Videos

Last Updated: May 15, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Published on: August 30, 2020

Area of Science:

Vascular Surgery
Haematology
Radiology

Background:

Pseudoaneurysms are uncommon complications in haemophilia patients.
Diagnosis is often prompted by a history of arterial trauma from various causes.
Historically, surgical ligation was the primary treatment.

Purpose of the Study:

To review the diagnosis and management of pseudoaneurysms in haemophilia.
To highlight the shift towards less invasive treatment modalities.
To emphasize the importance of early intervention and proper haemostasis.

Main Methods:

Literature review of reported pseudoaneurysm cases in haemophilia.
Discussion of diagnostic imaging techniques (Duplex ultrasonography, CT angiogram, conventional angiogram).
Overview of current and historical treatment options, including endovascular and surgical approaches.

Main Results:

Only 14 cases of pseudoaneurysms in haemophilia patients have been reported.
Most cases occurred in the musculoskeletal system.
Less invasive treatments like covered stents, compression, and ultrasound-guided thrombin injection are now favored over open surgery.

Conclusions:

Early diagnosis and treatment of pseudoaneurysms in haemophilia are crucial.
Endovascular treatments offer a minimally invasive option.
Effective haemostasis with factor concentrates and tranexamic acid is vital for all procedures, especially with advancements in managing patients with inhibitors.