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Published on: October 12, 2012
Erythema induratum of Bazin associated with Addison's disease: first description
Rodrigo Antonio Brandão Neto1, Jozélio Freire de Carvalho
1Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brazil. rodneto@gmail.com
Context:
Erythema induratum of Bazin (EIB) is considered to be a tuberculid reaction and consists of recurrent painful nodules. The differential diagnosis includes diseases like nodular vasculitis, perniosis, polyarteritis nodosa and erythema nodosum.
Case Report:
We report the case of a woman with EIB who developed Addison's disease during treatment with anti-tuberculosis drugs with good response to glucocorticoid replacement. The diagnosis was obtained through the clinical picture, positive tuberculin test and positive BCG (bacillus Calmette-Guérin) test on the histological sample. Anti-tuberculosis drugs and glucocorticoid replacement led to disappearance of the signs and symptoms.
Conclusions:
This is the first description of an association between EIB and Addison's disease. It should be borne in mind that tuberculosis is an important etiological factor for Addison's disease.
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