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Expression and function of Annexin II in lung cancer tissue
1First Affiliated Hospital of Xinxiang Medical University, Henan, China.
Objective:
To explore the expression of Annexin II and its relationship with the cell differentiation, proliferation in lung cancer.
Methods:
RT-PCR and Western blot assays were used to detect the expression of Annexin II in lung cancer tissues and cell lines.
Results:
Annexin II was significantly up-regulated in lung cancer tissues, and in lung cancer cell lines, Annexin II had higher mRNA and protein expressions.
Conclusions:
Annexin II is up-regulated in lung cancer, suggesting that the Annexin II has a potential value in the human lung cancer.
