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Updated: May 14, 2026

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System
Published on: April 23, 2021
Management Of Metastatic Breast Cancer (MBC)
1Department of Internal Medicine, King Fahd Hospital of the University, Eastern Province, Al-Khobar 31952, Saudi Arabia.
Unlabelled:
Chemotherapy of metastatic breast carcinoma so far, is not curative using the currently available chemotherapeutic, hormonal or biologic agents. The treatment of metastatic breast cancer is aimed mainly at alleviation of symptoms rather than cure. The first choice of therapy is dependent on patient age, performance status, hormone receptor status, human epidermal growth factor receptor-2 (HER-2), involvement of the viscera, or enrollment of patients in investigational trials. Combination of chemotherapeutic drugs showed an advantage for survival, tumor response and time to progression with adverse effects of these agents. It is very important, therefore, to balance between the benefits of treatment and the adverse effects and complication of therapy.
Keywords:
chemotherapy, metastatic, HER-2, breast, combination.
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