Approaches to management of adenocarcinoma following colocystoplasty

Primary adenocarcinoma of the urinary bladder is rare and more so is adenocarcinoma arising in an augmented colocystoplastic bladder. We present a case of adenocarcinoma developing in a urinary bladder after colocystoplasty which was managed by radical cystectomy with bilateral pelvic lymphadenectomy. The post-operative histopathology showed the lesion to be an Adenocarcinoma with spread to the pericolic lymphnodes and not the pelvic lymphnodes. There are no guidelines for bladder screening in these patients who appear to be at risk. Radical Cystectomy remains the treatment of choice. Though post op irradiation has been reported, its role is not clearly defined. Role of chemotherapy in the adjuvant setting is yet to be defined. Following this is the literature review and a discussion on Adenocarcinoma arising in a colocystoplastically augmented bladder.

Adenocarcinoma, urinary bladder, cystoplastically augmented bladder, radical cystectomy.