Peripheral artery disease in korean patients undergoing percutaneous coronary intervention: prevalence and
Eun Kyoung Kim1, Pil Sang Song, Jeong Hoon Yang
1Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Insights
Peripheral artery disease (PAD) affects 12.8% of patients undergoing percutaneous coronary intervention (PCI) for coronary artery disease (CAD). PAD is independently associated with left main and multivessel CAD, suggesting routine ABPI screening for PCI patients.
Area of Science:
- Cardiology
- Vascular Medicine
Background:
- Peripheral artery disease (PAD) is a significant indicator for risk stratification in patients with coronary artery disease (CAD).
- Understanding PAD prevalence and its correlation with CAD severity is crucial for comprehensive patient management.
Purpose of the Study:
- To determine the prevalence of PAD in patients with CAD undergoing percutaneous coronary intervention (PCI).
- To investigate the association between the ankle-brachial pressure index (ABPI) and the severity of CAD.
Main Methods:
- A cohort of 711 patients undergoing PCI for CAD between August 2009 and August 2011 were analyzed.
- Peripheral artery disease (PAD) was diagnosed using the ankle-brachial pressure index (ABPI).
- Coronary artery disease (CAD) severity was assessed using factors including left main disease, multivessel lesions, and SYNTAX score.
Main Results:
- The prevalence of PAD among patients undergoing PCI for CAD was 12.8%.
- Patients with PAD exhibited a higher incidence of left main coronary disease (14.3% vs. 5.8%) and multivessel lesions (74.9% vs. 52.1%).
- Left main CAD and multivessel CAD were independently associated with PAD (OR 2.954 and 2.321, respectively).
Conclusions:
- The study recommends implementing ABPI-based PAD screening for all patients undergoing PCI for CAD.
- Screening is particularly important for patients with severe CAD, given the independent association between PAD and complex coronary artery disease.
- Routine PAD screening can aid in better risk stratification and management of patients with coronary artery disease.
Abstract:
Peripheral artery disease (PAD) is an important marker for the risk stratification of patients with coronary artery disease (CAD). We investigated the prevalence of PAD in patients undergoing percutaneous coronary intervention (PCI) with CAD and the relationship between ankle-brachial pressure index (ABPI) and CAD severity. A total of 711 patients undergoing PCI for CAD from August 2009 to August 2011 were enrolled. PAD diagnosis was made using the ABPI. The prevalence of PAD was 12.8%. In PAD patients, mean values of right and left ABPI were 0.71 ± 0.15 and 0.73 ± 0.15. Patients with PAD had a higher prevalence of left main coronary disease (14.3% vs 5.8%, P = 0.003), more frequently had multivessel lesions (74.9% vs 52.1%, P < 0.001) and had higher SYNTAX score (18.2 ± 12.3 vs 13.1 ± 8.26, P = 0.002). Using multivariate analysis, we determined that left main CAD (OR, 2.954; 95% CI, 1.418-6.152, P = 0.004) and multivessel CAD (OR, 2.321; 95% CI, 1.363-3.953, P = 0.002) were both independently associated with PAD. We recommend that ABPI-based PAD screening should be implemented in all patients undergoing PCI with CAD, especially in severe cases.
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