Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Cranial Bones: Lateral View01:27

Cranial Bones: Lateral View

The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Introduction to the Skeletal System01:20

Introduction to the Skeletal System

The skeletal system is the central framework of the body, consisting of different connective tissues: bones, cartilage, tendons, and ligaments.
Components of the Skeletal System
Bone, or osseous tissue, is a hard connective tissue that forms an internal support structure for the human body. Bones shield vulnerable organs and soft tissue from external forces. For example, the vertebral bones protect and support the spinal cord.
Cartilage, a semi-rigid connective tissue found in regions such as...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Overview of the Skull01:08

Overview of the Skull

The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault. The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws.
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
Sutures of the Skull01:22

Sutures of the Skull

The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nutrient assimilation from puffer and tilapia aquaculture sludge by marine polychaete Neanthes acuminata (Ehlers, 1868): a way forward to solid waste management.

Environmental science and pollution research international·2026
Same author

Evaluation of the stability and cross-reactivity of zopiclone and eszopiclone using immunoassay kits.

The Journal of toxicological sciences·2026
Same author

Clinical differences between metformin-associated lactic acidosis and metformin-unrelated lactic acidosis: A descriptive study.

The American journal of emergency medicine·2026
Same author

Isolation of <i>Streptococcus mutans</i> in the gastrointestinal tract of corpses.

Journal of oral microbiology·2026
Same author

Application of RNA sequencing to cause-of-death investigation: A pilot study.

Legal medicine (Tokyo, Japan)·2025
Same author

Mefenamic Acid Poisoning Revisited: Central Nervous System Toxicity and Acute Kidney Injury.

Cureus·2025

Related Experiment Video

Updated: May 14, 2026

Skeletal Muscle Gender Dimorphism from Proteomics
09:29

Skeletal Muscle Gender Dimorphism from Proteomics

Published on: December 14, 2011

Gender differences in D-aspartic acid content in skull bone.

Aiko Torikoshi-Hatano1, Akira Namera, Hiroaki Shiraishi

  • 1Department of Forensic Medicine, Graduate School of Biomedical Sciences, Hiroshima University 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan. d093132@hiroshima-u.ac.jp

Hiroshima Journal of Medical Sciences
|January 25, 2013
PubMed
Summary

This study analyzed aspartic acid (Asp) racemization in human skull bones to estimate age at death. Researchers found significant differences in D-Asp levels between males and females, suggesting potential for sex determination in forensic investigations.

More Related Videos

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography
02:42

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Published on: January 17, 2025

Rapid Golgi Stain for Dendritic Spine Visualization in Hippocampus and Prefrontal Cortex
04:58

Rapid Golgi Stain for Dendritic Spine Visualization in Hippocampus and Prefrontal Cortex

Published on: December 3, 2021

Related Experiment Videos

Last Updated: May 14, 2026

Skeletal Muscle Gender Dimorphism from Proteomics
09:29

Skeletal Muscle Gender Dimorphism from Proteomics

Published on: December 14, 2011

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography
02:42

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Published on: January 17, 2025

Rapid Golgi Stain for Dendritic Spine Visualization in Hippocampus and Prefrontal Cortex
04:58

Rapid Golgi Stain for Dendritic Spine Visualization in Hippocampus and Prefrontal Cortex

Published on: December 3, 2021

Area of Science:

  • Forensic Anthropology
  • Biochemistry
  • Osteology

Background:

  • Personal identification of cadavers is crucial in forensic medicine.
  • Amino acid racemization, particularly in teeth, is an established method for age estimation.
  • Skull bones offer a potential alternative source for racemization analysis.

Purpose of the Study:

  • To investigate the feasibility of determining age at death using aspartic acid (Asp) racemization in human skull bones.
  • To analyze the correlation between Asp racemization and age, considering sex differences.
  • To assess the potential of Asp racemization as a forensic tool.

Main Methods:

  • Analysis of 61 human skull bone specimens (19 female, 42 male) from judicial autopsies.
  • Quantification of D-Asp, L-Asp, total protein, osteocalcin, and collagen I.
  • Application of logistic regression analysis for age and sex-based correlations.

Main Results:

  • Significant differences in the amount of D-Asp were observed between female and male skull bones (p = 0.021).
  • The amount of L-Asp showed no significant difference between sexes.
  • This indicates sex-specific variations in D-Asp levels within skull bones.

Conclusions:

  • Aspartic acid racemization in skull bones shows potential for forensic age estimation.
  • The observed sex-based differences in D-Asp levels may aid in sex determination.
  • Further research is warranted to refine this method for forensic applications.