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Recurrent exophytic meningioma in pregnancy
Michelle S Chow1, Philippe A Mercier, David A Omahen
1Department of Obstetrics & Gynecology, Foothills Hospital, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.
Pregnancy can accelerate meningioma growth and recurrence, as seen in a case of a recurrent meningioma in a woman during two pregnancies. Surgical treatment during pregnancy is feasible with a multidisciplinary approach.
Area of Science:
- Neuro-oncology
- Reproductive Medicine
Background:
- Meningiomas are typically slow-growing intracranial tumors.
- Hormonal fluctuations during pregnancy can influence meningioma growth and recurrence.
- This case highlights meningioma presentation and management during gestation.
Observation:
- A 35-year-old woman experienced a recurrent meningioma during two separate pregnancies.
- Symptoms included neurological decline and an enlarging forehead mass during the third trimester.
- Emergency craniotomy was performed for a massive extra-axial tumor.
Findings:
- Pathology confirmed a grade I meningioma with progesterone receptor positivity.
- The patient experienced significant blood loss during surgery.
- Both mother and fetus had favorable outcomes, with delivery at 38 weeks.
Implications:
- Pregnancy is a significant risk factor for accelerated meningioma growth and recurrence.
- Timely surgical intervention during pregnancy is possible and effective.
- A multidisciplinary team approach is crucial for managing meningiomas in pregnant patients.
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