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Spontaneous rupture of solid pseudopapillary neoplasm of the pancreas during pregnancy
Shih-Chiang Huang1, Tsung-Han Wu, Chien-Cheng Chen
1Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University School of Medicine, Taoyuan, Taiwan.
Background:
Spontaneous rupture of solid pseudopapillary neoplasm of the pancreas is an unusual complication during pregnancy.
Case:
At 19 weeks of gestation, a 29-year-old woman presented with a pancreatic mass and upper abdominal pain radiating to the back. On the third day of admission, shock and peritoneal signs developed. Exploratory laparotomy and subsequent subtotal pancreatectomy were performed for a bleeding tumor. Solid pseudopapillary neoplasm was confirmed by pathological examination. The patient delivered a healthy full-term girl vaginally. Eight months postoperatively, the clinical courses of both mother and infant have been uneventful.
Conclusion:
Ruptured solid pseudopapillary neoplasms can cause an acute abdomen during pregnancy. The expression of progesterone receptors in solid pseudopapillary neoplasm is a possible cause of this potentially devastating event.
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