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Updated: May 14, 2026

Activation and Conjugation of Soluble Polysaccharides using 1-Cyano-4-Dimethylaminopyridine Tetrafluoroborate (CDAP)
Published on: June 14, 2021
Experimental study of the hydration properties of homologous disaccharides
C Branca1, S Magazù, G Maisano
1Dipartimento di Fisica and INFM, Università di Messina, P.O. Box 55, C.da Papardo S. Sperone, 98166 Messina, Italy.
Abstract:
To get some insight into the hydration mechanisms of homologousdisaccharides, we report measurements on trehalose, maltose, and sucroseaqueous solutions. The interest on these systems is mainly due to theextraordinary properties of disaccharides and especially of trehalose, themost effective bio-protector against freezing and dehydration. To carry outthis study we have investigated the volumetric properties of the threedisaccharide solutions, by performing density and ultrasonic velocitymeasurements at different concentration and temperature values. Whatemerges from these studies is that trehalose shows, in comparison withmaltose and sucrose, the greatest structural sensitivity to temperaturechanges and the smallest values of the partial molar volume in all theinvestigated temperature range, this circumstance being indicative of a morepacked conformational arrangement.
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