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Terahertz time-domain spectroscopy of glucose and uric Acid
P C Upadhya1, Y C Shen, A G Davies
1Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge, CB3 0HE UK.
Abstract:
We report the use ofterahertz time-domain spectroscopy for thestudy of two therapeutic bio-molecules:glucose and uric acid. Terahertztransmission spectra of crystalline samplesof both molecules were measured between 0.1-3.0 THz using an evacuated spectroscopysystem. We propose that the stereo-isomersof glucose show spectral featuresoriginating from intermolecular vibrationalmodes, as do uric acid and its derivativemolecule, allantoin. In addition, wepresent a full temperature dependence ofthe terahertz absorption of L-glucose.
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