Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The DNA Helix01:16

The DNA Helix

Overview
The DNA Helix01:07

The DNA Helix

Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...
DNA Agarose Gel Electrophoresis02:35

DNA Agarose Gel Electrophoresis

Agarose gel electrophoresis is a laboratory technique commonly used to separate DNA fragments by size. However, it can also be used to isolate and purify DNA fragments using a gel extraction protocol.
Gel extraction follows five major steps: running gel electrophoresis to separate fragments, isolating the individual bands, extracting DNA from those bands, and removing the dye and salts from the extracted mixture to obtain pure DNA.
In cloning experiments, both the insert and vector DNA...
Polytene Chromosomes02:04

Polytene Chromosomes

Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...
Nucleic Acid Structure01:25

Nucleic Acid Structure

The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA has a double-helix structure. The...
Translesion DNA Polymerases02:10

Translesion DNA Polymerases

Translesion (TLS) polymerases rescue stalled DNA polymerases at sites of damaged bases by replacing the replicative polymerase and installing a nucleotide across the damaged site. Doing so, TLS allows additional time for the cell to repair the damage before resuming regular DNA replication.
TLS polymerases are found in all three domains of life - archaea, bacteria, and eukaryotes. Of the different classes of TLS polymerases, members of the Y family are fitted with specialized structures that...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experimental and numerical observation of dark and bright breathers in the band gap of a diatomic electrical lattice.

Physical review. E·2019
Same author

Impulse-induced generation of stationary and moving discrete breathers in nonlinear oscillator networks.

Physical review. E·2017
Same author

Energy localization and shape transformations in semiflexible polymer rings.

Physical review. E·2016
Same author

Ultradiscrete kinks with supersonic speed in a layered crystal with realistic potentials.

Physical review. E, Statistical, nonlinear, and soft matter physics·2015
Same author

Antagonism between granulocytic maturation and deacetylase inhibitor-induced apoptosis in acute promyelocytic leukaemia cells.

British journal of cancer·2014
Same author

From nodeless clouds and vortices to gray ring solitons and symmetry-broken states in two-dimensional polariton condensates.

Journal of physics. Condensed matter : an Institute of Physics journal·2014
Same journal

Multiscale frameworks for exploring protein energy landscapes: advances in theory and simulation.

Journal of biological physics·2026
Same journal

Mapping increased flexibility and conformational divergence via N-terminal helix-to-coil transition in USP12 mutant Y49N: a comprehensive in-detail normal mode simulation study.

Journal of biological physics·2026
Same journal

A thermodynamically consistent approach to modeling epithelial solute and water transport in the proximal convoluted tubule.

Journal of biological physics·2026
Same journal

Exploring the conformational space of the NorA efflux pump of Staphylococcus aureus: a microscale conventional molecular dynamics and metadynamics simulation approach.

Journal of biological physics·2026
Same journal

Coupled optical-thermal-chemical modeling of pulsed 808-nm ICG phototherapy using Monte Carlo photon transport.

Journal of biological physics·2026
Same journal

An innovative combinatorial coordination ratio perturbation approach for decoupled period-amplitude modulation.

Journal of biological physics·2026
See all related articles

Related Experiment Video

Updated: May 14, 2026

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

Charge Transport in Poly(dG)-Poly(dC) and Poly(dA)-Poly(dT) DNA Polymers.

D Hennig1, E B Starikov, J F R Archilla

  • 1Freie Universität Berlin, Fachbereich Physik, Institut für Theoretische Physik, Arnimallee 14, 14195 Berlin, Germany.

Journal of Biological Physics
|January 25, 2013
PubMed
Summary
This summary is machine-generated.

Synthetic DNA polymers show distinct charge transport properties. Poly(dG)-poly(dC) DNA exhibits efficient conductivity due to electron breathers, unlike poly(dA)-poly(dT) DNA, which has restrained charge transport.

More Related Videos

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures
08:30

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Published on: January 19, 2019

Studying DNA Looping by Single-Molecule FRET
11:27

Studying DNA Looping by Single-Molecule FRET

Published on: June 28, 2014

Related Experiment Videos

Last Updated: May 14, 2026

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures
08:30

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Published on: January 19, 2019

Studying DNA Looping by Single-Molecule FRET
11:27

Studying DNA Looping by Single-Molecule FRET

Published on: June 28, 2014

Area of Science:

  • Molecular Biophysics
  • Computational Chemistry
  • Condensed Matter Physics

Background:

  • Charge transport in synthetic DNA is crucial for molecular electronics.
  • Understanding electron-vibration coupling in DNA is key to predicting conductivity.
  • Previous studies suggest DNA can act as a semiconductor.

Purpose of the Study:

  • To investigate charge transport mechanisms in synthetic DNA polymers.
  • To model electron-vibration coupling and polaron dynamics.
  • To compare the conductivity of poly(dG)-poly(dC) and poly(dA)-poly(dT) DNA.

Main Methods:

  • Utilized a polaronlike model coupling electronic tight-binding with DNA bond vibrations.
  • Employed a quantum-chemical procedure to estimate electron-vibration coupling strengths.
  • Simulated polaron mobility to analyze charge transport properties.

Main Results:

  • Poly(dG)-poly(dC) DNA supports unidirectionally moving electron breathers, enabling efficient long-range conductivity.
  • Poly(dA)-poly(dT) DNA exhibits restrained polaron mobility, inhibiting charge transport.
  • Distinct transport properties were quantitatively identified between the two DNA types.

Conclusions:

  • Poly(dG)-poly(dC) DNA functions as a semiconducting nanowire with superior conductance.
  • Poly(dA)-poly(dT) DNA shows limited charge transport capabilities.
  • Results align with experimental findings on DNA conductivity.