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06:21
Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
Published on: May 27, 2016
Radiotherapy can cause haemostasis in bleeding skin malignancies
Helena Sung-In Jang1, Andrew Spillane, Frances Boyle
1St Vincent's Hospital Sydney, Victoria Street, Darlinghurst, NSW 2010, Australia.
Case Reports in Medicine
|January 25, 2013
Summary
Radiotherapy effectively achieved hemostasis in two patients with life-threatening bleeding from skin malignancies. This study is the first to report radiation-induced hemostasis for such conditions.
Area of Science:
- Oncology
- Dermatology
- Radiation Oncology
Background:
- Malignant bleeding from skin cancers can be life-threatening.
- Conventional treatments may not always control severe hemorrhage.
Purpose of the Study:
- To report the successful use of radiotherapy (RT) for hemostasis in bleeding skin malignancies.
- To evaluate RT as a treatment option for fatal exsanguination from skin cancer.
Main Methods:
- Two cases of bleeding skin malignancies were treated with radical or palliative intent.
- A dose of 20 Gray (Gy) in 5 fractions was administered to both patients.
Main Results:
- Radiotherapy successfully achieved hemostasis in both cases, preventing fatal exsanguination.
- Radiation-induced hemostasis was observed in these patients with skin malignancies.
Conclusions:
- Radiotherapy can be an effective modality for achieving hemostasis in bleeding skin malignancies.
- This represents the first reported instance of radiation-induced hemostasis in this clinical context.
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