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Related Concept Videos

Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
Stroke: Introduction and Types01:29

Stroke: Introduction and Types

A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...

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Updated: May 14, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Interaction between Sleep-Disordered Breathing and Acute Ischemic Stroke.

Seong Hwan Ahn1, Jin Ho Kim, Dong Uk Kim

  • 1Department of Neurology, College of Medicine, Chosun University, Gwangju, Korea.

Journal of Clinical Neurology (Seoul, Korea)
|January 25, 2013
PubMed
Summary

Sleep-disordered breathing (SDB) affects over 60% of acute ischemic stroke patients in Korea. SDB is linked to worse stroke outcomes and specific risk factors, suggesting a causal role.

Keywords:
acute cerebral infarctionprevalencesleep-disordered breathing

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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Area of Science:

  • Neurology
  • Sleep Medicine
  • Cardiovascular Research

Background:

  • Sleep-disordered breathing (SDB) is increasingly recognized as a significant factor in ischemic stroke.
  • Limited data exists on SDB prevalence, risk factors, and outcomes in Korean stroke patients.

Purpose of the Study:

  • To investigate the prevalence and characteristics of SDB in acute ischemic stroke patients in Korea.
  • To identify risk factors, stroke severity, and outcomes associated with SDB in this population.

Main Methods:

  • Prospective study of 293 acute ischemic stroke patients.
  • Assessment of cardiovascular risk factors, stroke severity (NIHSS, mRS), and sleep apnea-hypopnea index (AHI) via portable monitoring.
  • Evaluation of stroke lesion distribution and 3-month modified Rankin Scale (mRS) scores.

Main Results:

  • SDB prevalence was 63.1% (AHI ≥10), with higher rates in men.
  • SDB patients were older, had higher stroke severity scores (NIHSS, mRS), greater bulbar weakness, and more sleep-associated stroke onsets.
  • Alcohol consumption and atrial fibrillation were significant risk factors for SDB; stroke outcomes were poorer in SDB patients.

Conclusions:

  • SDB is highly prevalent in acute cerebral infarction in Korea.
  • Distinct risk factor profiles and sleep-related stroke onsets suggest SDB may contribute to ischemic stroke.
  • Increased SDB prevalence in stroke patients may be influenced by stroke severity and bulbar involvement.