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Disseminated Infection Caused by Eggerthella lenta in a Previously Healthy Young Man: A Case Report
Ahmad Salameh1, Stephen A Klotz, Tirdad T Zangeneh
1Department of Medicine, The University of Arizona Medical Center, University of Arizona, Tucson, AZ 85724, USA.
Abstract:
Anaerobic bacteria are the predominant normal flora of the mucous membranes which may cause life-threatening disseminated infections and are often difficult to culture from infected sites. Eggerthella (previously known as Eubacteria species) is an anaerobic, nonsporulating, nonmotile, Gram-positive rod that is found in the human colon and feces and has been isolated from various other clinical specimens. We report a case of complicated disseminated anaerobic bacterial infection with Eggerthella lenta in a healthy immunocompetent man causing multiple brain abscesses, liver abscesses, necrotizing pneumonia, and osteomyelitis of the left radial bone. He was successfully treated with empiric penicillin G and metronidazole.
Insights
Eggerthella lenta, an anaerobic bacterium, can cause severe disseminated infections. This case highlights successful treatment of a healthy individual with multiple abscesses using penicillin G and metronidazole.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Case Study
Background:
- Anaerobic bacteria are common human flora but can cause severe infections.
- Eggerthella lenta is an anaerobic Gram-positive rod found in the colon.
- Disseminated Eggerthella infections are rare, especially in immunocompetent individuals.
Purpose of the Study:
- To report a rare case of complicated disseminated Eggerthella lenta infection.
- To highlight the clinical presentation and management of such infections.
- To emphasize the importance of considering anaerobic bacteria in severe infections.
Main Methods:
- Case report of a healthy immunocompetent male patient.
- Detailed clinical presentation including multiple abscesses and osteomyelitis.
- Treatment with empiric antibiotics: penicillin G and metronidazole.
Main Results:
- The patient presented with multiple brain abscesses, liver abscesses, necrotizing pneumonia, and osteomyelitis.
- Eggerthella lenta was identified as the causative agent.
- Successful treatment outcome with the prescribed antibiotic regimen.
Conclusions:
- Eggerthella lenta can cause severe, life-threatening disseminated infections even in healthy individuals.
- Prompt diagnosis and appropriate antibiotic therapy are crucial for successful management.
- Penicillin G and metronidazole can be effective empiric treatments for Eggerthella infections.
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