Related Experiment Video
Updated: May 14, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
The efficacy of exposure and response prevention for geriatric obsessive compulsive disorder: a clinical case
Mairwen K Jones1, Bethany M Wootton, Lisa D Vaccaro
1The University of Sydney Anxiety Disorders Clinic, Discipline of Behavioural and Social Sciences in Health, Faculty of Health Sciences, The University of Sydney, Cumberland Campus, East Street, Lidcombe, NSW 2141, Australia.
Abstract:
Obsessive compulsive disorder (OCD) is one of the most frequently occurring psychiatric conditions in older adults. While exposure and response prevention (ERP) is considered the most effective psychological treatment for children and adults with OCD, research investigating its effectiveness for older adults is scarce. This clinical case study investigates the effectiveness of ERP in an 80-year-old man with a 65-year history of OCD. The client received 14 individual, 50-minute ERP treatment sessions. Clinician-based Y-BOCS scores reduced by 65% from 20 (moderate) at pretreatment to 7 (subclinical) at 7-month posttreatment followup. OCI-R total scores reduced by 45% from 38 at baseline to 21 at 7-month follow-up. Despite his long history of the disorder, ERP was effective and well tolerated. The application of ERP for older adults with OCD, including age-specific modifications that may be required for this treatment approach, is discussed.
Related Concept Videos
Obsessive-Compulsive Disorder
Operant Conditioning Intervention
In operant conditioning, behaviors that are...
Drug Dosing: Geriatric Patients
Pharmacodynamics in Geriatric Patients: Effects of Age
Behavior Therapy
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

