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Related Concept Videos

Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Requirements for Human Life01:26

Requirements for Human Life

The Earth and its atmosphere have provided humans with air, water, and food, but these are not the only requirements for survival. Humans also require a specific range of temperature and pressure that the Earth and its atmosphere provides.
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
Mechanisms of Heat Transfer01:14

Mechanisms of Heat Transfer

Heat transfer between the human body and its environment occurs through four main mechanisms: conduction, convection, radiation, and evaporation.
Conduction, accounting for approximately 3% of body heat loss at rest, is the process of exchanging heat between molecules of two materials in direct contact. This can result in both heat loss and gain. For instance, when the body is submerged in water, which conducts heat 20 times more effectively than air, it can either lose or gain significant heat.

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Related Experiment Video

Updated: May 14, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
08:22

A Preclinical Model of Exertional Heat Stroke in Mice

Published on: July 1, 2021

[Exertional heatstroke].

Cécile Salathé1, Cyril Pellaton, Laurent Vallotton

  • 1Service de Médecine Intensive Adulte et Centre des brûlés, CHUV,1011 Lausanne. cecile.salathe@chuv.ch

Revue Medicale Suisse
|January 26, 2013
PubMed
Summary
This summary is machine-generated.

Exertional heatstroke occurs when core body temperature exceeds 40°C during exercise, overwhelming the body's cooling mechanisms. Prompt cooling is crucial to prevent severe outcomes like organ damage and death.

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Related Experiment Videos

Last Updated: May 14, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
08:22

A Preclinical Model of Exertional Heat Stroke in Mice

Published on: July 1, 2021

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

Using an Ingestible Telemetric Temperature Pill to Assess Gastrointestinal Temperature During Exercise
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Using an Ingestible Telemetric Temperature Pill to Assess Gastrointestinal Temperature During Exercise

Published on: October 7, 2015

Area of Science:

  • Physiology
  • Environmental Medicine
  • Sports Medicine

Context:

  • Exertional heatstroke (EHS) is a critical medical condition characterized by a rapid rise in core body temperature (>40°C) accompanied by central nervous system dysfunction during physical exertion.
  • It arises when metabolic heat production during intense exercise surpasses the body's thermoregulatory capacity, particularly in hot and humid conditions.
  • Untrained individuals or those unacclimatized to heat are at higher risk.

Purpose:

  • To define exertional heatstroke and outline its pathophysiology.
  • To highlight the clinical manifestations and triggers of EHS.
  • To emphasize the critical importance of immediate cooling interventions.

Summary:

  • EHS results from a failure of thermoregulation due to excessive heat production during physical activity.
  • Pathological mechanisms include systemic inflammation and disseminated intravascular coagulation, potentially leading to multiorgan failure.
  • Rapid cooling is the cornerstone of emergency management to mitigate severe morbidity and mortality.

Impact:

  • Understanding the pathophysiology of EHS is vital for developing effective prevention and treatment strategies.
  • Early recognition and intervention, primarily rapid cooling, are essential to improve patient outcomes and reduce mortality.
  • This knowledge supports public health initiatives and athletic training protocols to minimize the incidence of exertional heatstroke.