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Updated: May 14, 2026
09:35
Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer
Published on: January 29, 2020
Synthesis of antioxidants for prevention of age-related macular degeneration
Dharati Joshi1, James Field, John Murphy
1Department of Chemistry, Columbia University, 3000 Broadway, New York, New York 10027, USA.
Journal of Natural Products
|January 26, 2013
Abstract:
Photooxidation of A2E may be involved in diseases of the macula, and antioxidants could serve as therapeutic agents for these diseases. Inhibitors of A2E photooxidation were prepared by Mannich reaction of the antioxidant quercetin. These compounds contain water-solubilizing amine groups, and several were more potent inhibitors of A2E photooxidation than quercetin.
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