Related Experiment Video
Updated: May 14, 2026

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
A case of neonatal human parechovirus encephalitis with a favourable outcome
Salvatore Renna1, Laura Bergamino1, Daniela Pirlo1
1Emergency Department of Paediatrics, G. Gaslini Children's Hospital, Genova, Italy.
Abstract:
Human parechoviruses (HPeVs) are a new family of neurotropic viruses that cause central nervous system (CNS) infections similar to enterovirus (EVs) meningoencephalitis in the neonatal period, resulting in white matter lesions that can be visualized with cranial ultrasonography and magnetic resonance imaging, and correlated to a large spectrum of neurological outcomes. HPeV should be suspected in neonates with signs and symptoms of sepsis-like illness or CNS disease. We report a case of neonatal HPeV encephalitis, diagnosed on the basis of clinical and radiological findings and HPeV RT-PCR, with a good neurological outcome.
Related Concept Videos
Arboviral Encephalitis
Encephalitis l: Introduction
Encephalitis ll: Pathophysiology
Viral Meningitis
Bacterial Meningitis I: Introduction
Cytomegalovirus Disease
