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Updated: May 14, 2026

A Structured Approach to Extubation in Mechanically Ventilated Rats
Published on: July 18, 2025
Modern non-invasive mechanical ventilation turns 25
Salvador Díaz Lobato1, Sagrario Mayoralas Alises
1Servicio de Neumología, Hospital Universitario Ramón y Cajal, Madrid, España.
Modern non-invasive mechanical ventilation began in 1987, revolutionizing respiratory medicine. This review highlights key advancements in this vital therapy over the past 25 years.
Area of Science:
- Respiratory Medicine
- Medical Technology
Background:
- Non-invasive mechanical ventilation (NIMV) has a history exceeding 100 years.
- The development of modern NIMV is attributed to a 1987 description of nasal mask ventilation for Duchenne's disease.
Observation:
- The period since 1987 has seen exponential growth in NIMV utilization.
- Significant technological advancements have occurred in NIMV devices and applications.
Findings:
- The review focuses on the major milestones in NIMV development.
- The impact of NIMV on respiratory care has been substantial.
Implications:
- Understanding NIMV's history provides context for current respiratory support strategies.
- Continued innovation in NIMV promises further advancements in patient care.
- NIMV has significantly contributed to the progress of respiratory medicine.
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