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Related Experiment Videos

Development of a biocompatible hermetically sealed electrical feedthrough.

P D Diegel1, J W Holfert, K R Crump

  • 1Artificial Heart Research Laboratory, University of Utah, Salt Lake City.

Biomedical Sciences Instrumentation
|January 1, 1990
PubMed
Summary

A novel biocompatible electric wire feedthrough prevents fluid leakage in implantable devices like artificial hearts. This innovation enhances the reliability of totally implantable artificial hearts (TAH) and ventricular assist devices (VAD).

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Area of Science:

  • Biomaterials Engineering
  • Medical Device Technology
  • Implantable Devices

Background:

  • Early prototypes of totally implantable artificial hearts (TAH) and ventricular assist devices (VAD) experienced failures due to fluid transfer.
  • A critical component for implantable electronic devices is a reliable method for passing electrical signals through the device's housing without compromising hermeticity.

Purpose of the Study:

  • To develop and characterize a new biocompatible, hermetically sealed electric wire feedthrough for TAH and VAD applications.
  • To prevent fluid transfer across the housing wall, thereby improving the longevity and reliability of implantable cardiac devices.

Main Methods:

  • Designed a feedthrough utilizing a rigid polyurethane (Isoplast 301) housing and a low-viscosity silicone oil (decamethyltetrasiloxane) hydraulic fluid.

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  • Employed external and internal wires insulated with segmented polyurethane (Biomer), connected via a conductive pin.
  • Encapsulated the pin and wire connections in Biomer to create a leak-free barrier.

    • Main Results:

    • The developed feedthrough successfully prevents fluid transfer between the internal and external environments of the implantable device.
    • The Biomer encapsulation effectively seals the wire connections and conductive pin, ensuring a hermetic barrier.
    • The design allows for the passage of electric current through the housing wall without compromising device integrity.

    Conclusions:

    • The new biocompatible hermetically sealed electric wire feedthrough is a viable solution for preventing fluid leakage in implantable cardiac devices.
    • This technology significantly enhances the reliability and safety of totally implantable artificial hearts (TAH) and ventricular assist devices (VAD).