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Determination of underlying causes in asymptomatic, early-stage renal diseases by dipstick test

Mesut Okur1, Sukru Arslan, Ahmet Sami Guven

  • 11Department of Pediatrics, School of Medicine, Duzce University, Duzce, 2Department of Pediatric Nephrology, 3Department of Pediat- rics; School of Medicine, Yuzuncu Yil University, Van; Turkey.

Medicinski Glasnik : Official Publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina
|January 26, 2013
PubMed

Insights

Screening healthy school children for hematuria and proteinuria can help prevent chronic kidney disease. Persistent findings warrant further investigation for underlying causes like renal stones or infections.

Area of Science:

  • Pediatric Nephrology
  • Urology
  • Public Health Screening

Background:

  • Early detection of kidney abnormalities in children is crucial for preventing chronic kidney disease.
  • Urinary abnormalities like hematuria and proteinuria can be indicators of underlying renal pathology.

Purpose of the Study:

  • To screen healthy school-aged children for hematuria and proteinuria using urine strips.
  • To identify children with persistent urinary abnormalities for further evaluation.
  • To determine the incidence of these conditions in a specific pediatric population.

Main Methods:

  • A urine screening was conducted on 1848 healthy school-aged children (7-14 years) in eastern Turkey in 2008.
  • Children with persistent hematuria and/or proteinuria were referred for specialist pediatric nephrology examination.
  • Diagnostic workups were performed on referred cases to identify underlying etiologies.

Main Results:

  • The incidence of isolated hematuria was 4.9%, isolated proteinuria 0.8%, and combined hematuria-proteinuria 0.5%.
  • Persistence rates were 11.9% for isolated hematuria and 40% for combined hematuria-proteinuria.
  • Identified causes included renal stones, hypercalciuria, urinary tract infections, vesicoureteral reflux, atrophic kidney, and IgA nephropathy.

Conclusions:

  • Persistent hematuria in children necessitates investigation for conditions such as renal stones, hypercalciuria, and urinary tract infections.
  • Urine strip screening is a valuable tool for identifying children at risk for kidney disease.
  • Prompt referral and examination of persistent urinary abnormalities can lead to early diagnosis and management.
Abstract

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