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Secretomes: the fungal strike force
Vincent Girard1, Cindy Dieryckx, Claudette Job
1Bayer CropScience Joint Laboratory, CNRS, University Lyon 1, 14 impasse Pierre Baizet, Lyon, France. vincent.girard@bayer.com
Proteomics
|January 26, 2013
Summary
Fungal secretomes exhibit remarkable diversity, necessitating comprehensive characterization. Understanding this variability is crucial for controlling fungal pathogens and developing new applications.
Area of Science:
- Microbiology
- Mycology
- Biochemistry
Background:
- Microorganisms, including bacteria and fungi, possess an essential exodigester function.
- Environmental pressures drive the adaptation of microbial secretomes, leading to diverse compositions.
- Fungal secretomes are particularly variable, even within species.
Purpose of the Study:
- To review the extraordinary variability of fungal secretomes.
- To emphasize the necessity of fully characterizing secretome components.
- To understand mechanisms of secretome plasticity and develop applications for disease control.
Main Methods:
- Literature review focusing on fungal secretomes.
- Analysis of existing data on secretome composition and variability.
- Discussion of environmental influences on secretome evolution.
Main Results:
- Fungal secretomes display significant heterogeneity.
- Environmental selection pressures result in diverse secretome architectures.
- Variability exists even at the intraspecies level.
Conclusions:
- Comprehensive characterization of fungal secretomes is essential.
- Understanding secretome plasticity can lead to novel applications.
- This knowledge is vital for controlling fungal pathogens and related diseases.
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