Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

New passive perfusion PTCA catheter.

C J White1, S R Ramee, A K Banks

  • 1Cardiac Catheterization Laboratory, Ochsner Clinic, New Orleans, LA.

Catheterization and Cardiovascular Diagnosis
|April 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Roadmap for the expression of canonical and extended endocannabinoid system receptors and metabolic enzymes in peripheral organs of preclinical animal models.

Physiological reports·2024
Same author

Roadmap For The Expression Of Canonical and Extended Endocannabinoid System Receptors and Proteins in Peripheral Organs of Preclinical Animal Models.

bioRxiv : the preprint server for biology·2023
Same author

Emission Characteristics and Effect of Battery Drain in "Budget" Curing Lights.

Operative dentistry·2015
Same author

Persistently increased expression of the transforming growth factor-β1 gene in human vascular restenosis: Analysis of 62 patients with one or more episode of restenosis.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
Same author

Current status of adult spinal deformity.

Global spine journal·2014
Same author

Sustained in vivo release from imprinted therapeutic contact lenses.

Journal of controlled release : official journal of the Controlled Release Society·2011

A new passive perfusion balloon catheter allows significantly longer coronary angioplasty inflations compared to standard balloons. This innovative device maintained excellent distal blood flow, reducing risks like ST segment deviation and ventricular fibrillation.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Biomedical Engineering

Background:

  • Prolonged balloon inflations are crucial in percutaneous coronary angioplasty (PCA) but limited by ischemia.
  • Standard angioplasty balloons can cause significant electrocardiographic changes and arrhythmias.
  • The need for improved devices to facilitate extended balloon use during PCA is critical.

Purpose of the Study:

  • To compare the efficacy and safety of a novel passive perfusion balloon catheter against a standard balloon catheter.
  • To evaluate the impact of prolonged balloon inflations on myocardial ischemia and distal perfusion.
  • To assess the potential of the perfusion balloon to extend inflation times during PCA.

Main Methods:

  • A comparative study in 24 miniature coronary arteries using alternating inflations of a passive perfusion balloon and a standard balloon.

Related Experiment Videos

  • Inflation endpoints included 2 mm ST segment deviation, ventricular fibrillation, or 30 minutes.
  • Distal coronary blood flow was assessed using the TIMI scale (0-3) via contrast injections.

    • Main Results:

    • Passive perfusion balloon inflations averaged 27.2 minutes, significantly longer than standard balloon inflations (3.1 minutes; P < 0.001).
    • ST segment deviation occurred less frequently with the perfusion balloon (3/11) compared to the standard balloon (11/13).
    • Ventricular fibrillation occurred in 2/13 standard balloon inflations but none with the perfusion balloon. Excellent distal flow (2.7/3) was maintained with the perfusion balloon.

    Conclusions:

    • The passive perfusion balloon catheter enables significantly prolonged balloon inflations in PCA.
    • This improved device maintains excellent distal coronary artery perfusion, mitigating ischemic complications.
    • The passive perfusion balloon represents a promising advancement for complex percutaneous coronary interventions.