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Kathon CG and cosmetic products
1Ministry of Environment, National Environmental Research Institute, Søborg, Denmark.
Contact Dermatitis
|March 1, 1990
Summary
Kathon CG is present in 42% of Danish cosmetics, with a disturbed preservative ratio found in many products, especially leave-on types. This ratio may be affected by chemical reactions within cosmetic formulations.
Area of Science:
- Cosmetic Science
- Analytical Chemistry
- Dermatology
Background:
- Kathon CG is a widely used preservative in cosmetic products.
- The efficacy and safety of cosmetic preservatives are critical for consumer health.
- Understanding preservative stability and composition is essential for product quality control.
Purpose of the Study:
- To determine the prevalence of Kathon CG in Danish cosmetic products.
- To analyze the ratio of chloromethylisothiazolinone (CMI) to methylisothiazolinone (MI) in Kathon CG preserved cosmetics.
- To investigate factors potentially disturbing the CMI:MI ratio.
Main Methods:
- Analysis of 156 commonly used cosmetic products in Denmark.
- Quantification of Kathon CG and its components (CMI, MI).
- Assessment of the CMI:MI ratio in preserved products.
Main Results:
- Kathon CG was detected in 42% of the analyzed cosmetic products.
- Higher prevalence in "rinse-off" (48%) compared to "leave-on" (31%) products.
- A disturbed CMI:MI ratio was observed in 41% of products containing Kathon CG, notably higher in "leave-on" (73%) than "rinse-off" (29%) types.
Conclusions:
- The CMI:MI ratio in Kathon CG can be significantly altered in cosmetic formulations.
- Chemical interactions between isothiazolinones and other cosmetic ingredients may disturb the ratio.
- Findings have implications for cosmetic safety, allergic reactions, and preservative efficacy testing.