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GPCR Retreat 2012: timing is everything.
Peter Chidiac1, Terence E Hébert
1Department of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada. peter.chidiac@schulich.uwo.ca
Journal of Receptor and Signal Transduction Research
|January 29, 2013
Summary
The 13th Annual Great Lakes GPCR Retreat highlighted advances in G protein-coupled receptor (GPCR) research, celebrating Nobel Prize-winning work on receptor structure and function.
Area of Science:
- Biochemistry and Molecular Pharmacology
- Neuroscience
- Oncology
Background:
- The 13th Annual Great Lakes GPCR Retreat convened investigators from the US and Canada.
- Discussions focused on G protein-coupled receptors (GPCRs), crucial for cellular signaling.
- The event coincided with the Nobel Prize in Chemistry awarded for GPCR research.
Framework:
- The meeting explored the physiological roles of GPCRs in the nervous system, circadian biology, and cancer.
- Sessions addressed the cellular and molecular aspects of GPCR, G protein, and effector structure and function.
- Emphasis was placed on GPCR regulation and trafficking.
Implementation:
- The retreat fostered collaboration among researchers from Michigan, Ontario, and Québec.
- Discussions aimed to bridge the gap between molecular pharmacology and in vivo applications.
- A tribute honored Marc Caron's pioneering contributions to GPCR research.
Implications:
- The conference underscored the significance of GPCRs in diverse physiological processes.
- Advances in understanding GPCR structure and function are paving the way for new therapeutic strategies.
- The event highlighted the growing international focus on GPCR research and its clinical relevance.

