Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Homeostatic Imbalance01:10

Homeostatic Imbalance

Homeostasis is the maintenance of a stable internal environment within the body, which is crucial for the proper functioning of cells, tissues, organs, and organ systems. The body has various control mechanisms that work together to regulate various physiological parameters such as temperature, blood pressure, pH balance, and fluid balance, to name a few. These control mechanisms are based on feedback loops that can be either positive or negative.
However, sometimes these feedback loops fail,...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
Acute Inflammation III: Local and Systemic Effects01:25

Acute Inflammation III: Local and Systemic Effects

Acute inflammation produces a coordinated set of local and systemic changes that limit injury, eliminate pathogens, and initiate repair. These responses arise within minutes of infection, trauma, or chemical insult and are driven by vascular alterations and leukocyte-derived mediators. When the stimulus resolves, the reaction typically abates within days.Local EffectsAt the site of injury, arteriolar vasodilation increases blood flow, resulting in redness and warmth. Simultaneously, increased...
Cellular Injury I: Introduction01:00

Cellular Injury I: Introduction

Cellular injury occurs when a cell cannot maintain homeostasis or adapt to stressors such as hypoxia, toxins, or trauma. Depending on severity and duration, injury may be reversible, allowing recovery, or irreversible, leading to cell death.General Mechanisms of Cell InjuryAlthough causes vary, most cellular injuries arise from a few key mechanisms that disrupt essential functions and often amplify one another. Cell survival depends on the extent and balance of these disturbances.ATP depletion...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fluid management of acute kidney injury.

Current opinion in critical care·2024
Same author

Curriculum Using the In-Situ Operating Room Setting.

Journal of surgical education·2017
Same author

Awake Craniotomy: A New Airway Approach.

Anesthesia and analgesia·2015
Same author

Noninvasive respiratory support in the perioperative period.

Current opinion in anaesthesiology·2013
Same author

Postoperative noninvasive ventilation.

Anesthesiology clinics·2012
Same author

Clinical review: Special populations--critical illness and pregnancy.

Critical care (London, England)·2011

Related Experiment Video

Updated: May 14, 2026

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma
04:20

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma

Published on: July 28, 2020

Trauma and aggressive homeostasis management.

Patrick J Neligan1, Dimitry Baranov

  • 1Department of Anaesthesia and Intensive Care, Galway University Hospitals, Galway, Ireland. Patrick.neligan@hse.ie

Anesthesiology Clinics
|January 29, 2013
PubMed
Summary

Maintaining bodily stability (homeostasis) is crucial for trauma patients. This review questions current methods for managing hyperglycemia, lactic acidosis, and hypothermia during acute care, challenging conventional wisdom.

More Related Videos

Pseudofracture: An Acute Peripheral Tissue Trauma Model
10:08

Pseudofracture: An Acute Peripheral Tissue Trauma Model

Published on: April 18, 2011

Integrated Compensatory Responses in a Human Model of Hemorrhage
07:57

Integrated Compensatory Responses in a Human Model of Hemorrhage

Published on: November 20, 2016

Related Experiment Videos

Last Updated: May 14, 2026

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma
04:20

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma

Published on: July 28, 2020

Pseudofracture: An Acute Peripheral Tissue Trauma Model
10:08

Pseudofracture: An Acute Peripheral Tissue Trauma Model

Published on: April 18, 2011

Integrated Compensatory Responses in a Human Model of Hemorrhage
07:57

Integrated Compensatory Responses in a Human Model of Hemorrhage

Published on: November 20, 2016

Area of Science:

  • Physiology
  • Critical Care Medicine
  • Trauma Surgery

Background:

  • Homeostasis is the body's ability to maintain a stable internal state through regulatory mechanisms.
  • Trauma and surgery trigger a significant metabolic and neuroendocrine stress response in patients.
  • Understanding this stress response is vital for effective patient management.

Purpose of the Study:

  • To review key issues concerning homeostasis in acute trauma care.
  • To examine the relationship between the stress response and hyperglycemia, lactic acidosis, and hypothermia.
  • To critically evaluate current approaches to restoring homeostasis in trauma patients.

Main Methods:

  • Literature review focusing on homeostasis and the stress response in trauma.
  • Analysis of existing research on hyperglycemia, lactic acidosis, and hypothermia in trauma patients.
  • Discussion of conventional versus evidence-based management strategies.

Main Results:

  • The stress response significantly impacts metabolic and endocrine functions in trauma patients.
  • Hyperglycemia, lactic acidosis, and hypothermia are common and critical issues in acute trauma care.
  • Current management strategies for these conditions may not align with optimal homeostatic restoration.

Conclusions:

  • Conventional approaches to managing hyperglycemia, lactic acidosis, and hypothermia in trauma patients warrant re-evaluation.
  • A deeper understanding of the neuroendocrine stress response is needed for improved homeostatic control.
  • Evidence-based strategies are essential for optimizing acute care and patient outcomes in trauma.