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Updated: May 14, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Suicide attempts and psychological risk factors in patients with bipolar and unipolar affective disorder
Joanna Pawlak1, Monika Dmitrzak-Węglarz, Maria Skibińska
1Department of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poland. joanna.pawlak@gmail.com
Abstract:
Suicide is an important clinical problem in psychiatric patients. The highest risk of suicide attempts is noted in affective disorders. The aim of the study was looking for suicide risk factors among personality dimensions and value system in patients with diagnosis of unipolar and bipolar affective disorder (n=189 patients, n=101 controls). To establish the diagnosis, we used SCID (Structured clinical interview for diagnostic and statistical manual of mental disorders, fourth edition) questionnaire, TCI (Temperament and Character Inventory) questionnaire and Value Survey--to assess the personality. The main limitations of the study are number of participants, lack of data about stressful life events and treatment with lithium. Novelty seeking and harm avoidance dimensions constituted suicide attempt risk factors in the group of patients with affective disorders. Protective role of cooperativeness was discovered. Patients with and without suicide attempt in lifetime history varied in self-esteem position in Value Survey.
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