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Updated: May 14, 2026

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Published on: May 12, 2011

[Optic nerve schwannoma].

S Leruez¹, P Gohier, P Menei

¹Service d'ophtalmologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 09, France. stephanieleruez@hotmail.fr

Journal Francais D'Ophtalmologie

|January 29, 2013

Summary

This summary is machine-generated.

This case report details a rare orbital schwannoma, a tumor typically affecting peripheral nerves, found on the optic nerve. Its similar appearance to cavernous hemangioma on imaging can lead to misdiagnosis.

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Area of Science:

Ophthalmology
Neuropathology
Neurosurgery

Background:

Schwannomas are tumors arising from Schwann cells, typically found in peripheral nerves.
Optic nerve schwannomas are exceptionally rare due to the optic nerve's limited Schwann cell population.

Observation:

A 65-year-old presented with five years of progressive, painless right proptosis.
Magnetic resonance imaging revealed an intraconal orbital mass.
Radiological findings were initially consistent with a cavernous hemangioma.

Findings:

Surgical resection and subsequent histopathology confirmed the mass as an optic nerve schwannoma.
The tumor likely arose from aberrant sympathetic nerve fibers or ectopic cells within the optic nerve sheath.

Implications:

Optic nerve schwannomas present a diagnostic challenge due to their rarity and potential to mimic more common orbital tumors like cavernous hemangiomas.
Accurate preoperative diagnosis is crucial for appropriate surgical planning and management of optic nerve tumors.