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Assessing the intelligence of children with chronic kidney diseases

Mostafa Amr1, Abdel Hady El-Gilany, Ashraf Bakr

  • 1Department of Psychiatry, Mansoura University, Mansoura, Egypt. mostafapsy@yahoo.com

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|January 29, 2013
PubMed

Insights

Children with chronic kidney disease (CKD) show lower intelligence scores. Both predialysis and dialysis patients performed worse than healthy children, indicating a need for early neurocognitive assessment and educational support.

Area of Science:

  • Pediatric Nephrology
  • Neuropsychology
  • Developmental Pediatrics

Background:

  • Chronic kidney disease (CKD) affects children globally.
  • Cognitive function in pediatric CKD patients requires further investigation.
  • Early identification of neurocognitive deficits is crucial for intervention.

Purpose of the Study:

  • To assess intelligence levels in children with CKD stage 5.
  • To compare cognitive function between predialysis, dialysis, and healthy children.
  • To understand the impact of CKD on neurocognitive development.

Main Methods:

  • Utilized the Wechsler Intelligence Scale for Children (WISC) for assessment.
  • Included three groups: 12 children with CKD stage 5 on hemodialysis, 12 in predialysis stage, and 12 healthy controls.
  • Analyzed verbal, performance, and full-scale IQ scores, along with arithmetic subtest performance.

Main Results:

  • Children with CKD (predialysis and dialysis) exhibited significantly lower mean scores in verbal, performance, and full-scale IQ compared to healthy controls.
  • Predialysis children scored significantly lower on arithmetic subtests than children undergoing dialysis.
  • Cognitive impairments are evident in children with varying stages of CKD.

Conclusions:

  • Pediatric CKD is associated with significant neurocognitive deficits.
  • Early and comprehensive neurocognitive assessments are vital for children with CKD.
  • Tailored educational interventions are necessary to address the challenges posed by CKD-related cognitive impairments.

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