Related Experiment Video
Updated: May 14, 2026

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
Published on: November 30, 2016
Providing nutritional support for patients with cancer cachexia
Elizabeth McCreery1, John Costello
1Pennine Acute Hospitals NHS Trust, Manchester, UK.
Cancer cachexia, a severe condition causing weight loss and poor quality of life, affects many advanced cancer patients. Effective management requires a multidisciplinary approach focusing on nutritional and social support.
Area of Science:
- Oncology
- Clinical Nutrition
- Palliative Care
Background:
- Malnutrition is a common secondary diagnosis in advanced cancer, affecting up to 85% of patients.
- Cancer cachexia, characterized by anorexia and weight loss, significantly impacts quality of life and survival.
- Healthcare professionals often lack understanding and effective strategies for managing cancer cachexia.
Purpose of the Study:
- To examine the quality of life for advanced cancer patients experiencing cachexia.
- To review the etiology, management, and treatment strategies for cancer cachexia.
- To highlight the benefits of the Macmillan approach for weight and eating in cachexia management.
Main Methods:
- Literature review on cancer cachexia, quality of life, and nutritional support.
- Analysis of current treatment methods and management strategies.
- Emphasis on the Macmillan approach's focus on social aspects of eating and weight gain.
Main Results:
- Cancer cachexia presents significant challenges in nutritional support for end-of-life patients.
- A multidisciplinary team approach is crucial for comprehensive cachexia management.
- The Macmillan approach offers a valuable framework by addressing social factors in eating and weight.
Conclusions:
- Effective management of cancer cachexia requires a holistic approach beyond basic dietary needs.
- Understanding and addressing the psychosocial aspects of eating is vital for improving patient and carer well-being.
- Further research and education are needed to improve healthcare professionals' ability to manage cancer cachexia.
Related Concept Videos
Chronic Kidney Disease III: Interprofessional Care
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Survival Analysis
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...