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MR findings in neonatal herpes simplex encephalitis type II
D Enzmann1, Y Chang, G Augustyn
1Department of Diagnostic Radiology, Stanford University Medical Center, CA 94305.
Journal of Computer Assisted Tomography
|May 1, 1990
Summary
Neonatal herpes simplex encephalitis (HSE) type II shows characteristic CT findings, but MR findings are newly described. This report details serial MR and CT scans, explaining the cause of increased gray matter density.
Area of Science:
- Neurology
- Radiology
- Pediatrics
Background:
- Neonatal herpes simplex encephalitis (HSE) type II is a severe condition affecting newborns.
- Previous studies have detailed computed tomography (CT) findings in neonatal HSE type II.
- Magnetic resonance (MR) findings in neonatal HSE type II have not been well-described.
Observation:
- Early CT findings in neonatal HSE type II can be subtle and challenging to detect.
- As the disease progresses, a characteristic increase in cortical gray matter density becomes apparent on CT scans.
- This case report presents serial MR and CT imaging findings in a neonate with HSE type II.
Findings:
- The study describes the evolution of MR and CT findings in neonatal HSE type II.
- Neuropathologic verification supports the imaging observations.
- The findings suggest an etiology for the increased gray matter density seen on CT, differentiating it from hemorrhage or calcification.
Implications:
- This research provides crucial insights into the MR characteristics of neonatal HSE type II.
- Understanding these imaging findings can aid in earlier and more accurate diagnosis of this serious condition.
- The study contributes to the differentiation of imaging features in neonatal brain infections.