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Identification of a novel HLA-A allele, A*02:357, in a Chinese individual

M Dai1, Y-P Su, A Sun

  • 1Institute of Transfusion Medicine of Yueyang, The Central Blood Station of Yueyang City, Yueyang, Hunan, China. daimin0017993@126.com

Tissue Antigens
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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...