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Related Experiment Videos

Histopathology of root surface caries.

P Schüpbach1, B Guggenheim, F Lutz

  • 1Department of Oral Microbiology and General Immunology, University of Zürich, Switzerland.

Journal of Dental Research
|May 1, 1990
PubMed
Summary

Root caries involves distinct patterns of demineralization and bacterial spread in cementum and dentin. Arrested root caries shows mineralization, suggesting remineralization is possible, supporting non-invasive treatments.

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Dental caries in rats associated with Candida albicans.

Caries research·2011

Area of Science:

  • Dental Research
  • Oral Pathology
  • Caries Science

Background:

  • Root caries is a prevalent oral disease affecting cementum and dentin.
  • Understanding the histopathology of active and arrested root caries is crucial for effective treatment strategies.

Purpose of the Study:

  • To examine the histopathology of active and arrested human root caries using various optical methods.
  • To differentiate mechanisms of lesion progression and arrestment in dental structures.

Main Methods:

  • Histopathological examination of extracted human teeth with root caries.
  • Utilized different optical methods to analyze cementum and dentin lesions.
  • Distinguished lesion patterns based on severity, dentin sclerosis, and calculus presence.

Main Results:

  • Identified three distinct patterns of initial cementum and dentin lesions.
  • Observed massive lateral bacterial spread into intertubular dentin in advanced lesions.
  • Arrested lesions showed intertubular dentin mineralization and sclerosed dentinal tubules, some with bacterial remnants.

Conclusions:

  • Root caries arrestment and remineralization depend on dentinal tubule sclerosis, bacterial infection degree, lesion progression, and location.
  • Remineralization of active root caries lesions is suggested to be possible.
  • Findings support the concept of non-invasive treatment for root caries, avoiding cavitation.

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