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Updated: May 14, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Retinal and choroidal findings in oxalate retinopathy using EDI-OCT
Bryan M Roth1, Alex Yuan, Justis P Ehlers
1Vitreoretinal Service, Cole Eye Institute, Cleveland Clinic,Cleveland, Ohio 44195 , USA.
Abstract:
A 55-year-old woman with extensive retinal crystalline deposition secondary to primary hyperoxaluria presented with bilateral loss of vision secondary to oxalate retinopathy. Enhanced depth imaging optical coherence tomography revealed intraretinal, subretinal, and intraretinal and subretinal pigment epithelium, and choroidal focal hyperreflective structures consistent with both neurosensory and uveal deposition of oxalate crystals. Serial optical coherence tomography revealed continued crystalline deposition with progressive retinal atrophy.
